Why Use Ariessence PDGF+ for Under-Eye Rejuvenation?
- Evolving Aesthetics
- Aug 12, 2025
- 2 min read
Updated: Aug 13, 2025
At Evolving Aesthetics here in Orlando, we focus on creating natural, refreshed results—never overdone. One of the newest and most exciting treatments for the delicate under-eye area is ariessence PDGF+ (platelet-derived growth factor). Unlike traditional dermal fillers that simply “fill” hollow areas like under eyes, PDGF stimulates your body’s own regenerative healing for long-lasting improvement in skin quality.
What is PDGF?
Platelet-Derived Growth Factor (PDGF) is a naturally occurring growth factor found in the body and released by platelets during healing. It signals repair. It tells local skin cells to start the process of repair, collagen production, and tissue regeneration. Ariessence PDGF+ features a biologic approach. Because it’s derived from the body’s own biology, PDGF works with your natural processes instead of masking concerns.
How PDGF Works For Tear Trough
The tear trough (the area just beneath the eyes) can lose volume, elasticity, and smoothness over time. PDGF can help this tricky area:
Injection & Targeting: PDGF is carefully injected into the delicate under-eye area at the dermal–subdermal junction for precise placement.
Cellular Activation: Once placed, PDGF binds to receptors on fibroblasts, pericytes, and endothelial cells, activating key healing pathways (MAPK, PI3K/AKT) that drive tissue regeneration.
Collagen & ECM Remodeling: Stimulates type I & III collagen synthesis to improve skin thickness and elasticity, and encourages production of extracellular matrix (ECM) components such as elastin and hyaluronic acid, which keep skin smooth and hydrated.
How PDGF Helps with Dark Circles
Many dark circles are caused by poor circulation or thinning skin. Targeting this area with ariessence PDGF+ addresses both through:
Vascular Support: Promotes new capillary growth (angiogenesis) for healthier skin tone and oxygenation.
Improved Microcirculation: Helps reduce discoloration from stagnant blood flow.
Long-Term Regeneration: Over 4–12 weeks, patients often notice:
A smoother transition between the lower eyelid and cheek
Firmer, less crepey under-eye skin
Reduced shadowing from hollowing
When To Choose PDGF For Under Eye Instead of Filler
While dermal fillers can work beautifully in the right areas, the under-eye region is notoriously tricky. Working with ariessence PDGF+ offers distinct advantages:
No Tyndall effect (the blue hue that can occur with filler)
No long-term puffiness or migration risk
Targets skin quality and structure, not just volume
Minimal to zero risk of vascular occlusion since it’s a biologic, not a particulate filler
If you want a refreshed, natural look without the risks associated with under-eye filler, ariessence PDGF+ offers a regenerative, science-backed solution. We work with each client for a fully tailored approach that helps them achieve a natural and refreshed look that meets their individual goals. Book your appointment to discuss PDGF and other aesthetic services today.
